Priority Setting Partnership
Patients and clinicians unite to set shared research priorities for chronic or recurrent urinary tract infections
AMR Action UK is proud to have funded a dedicated project
to bring patients and clinicians together to set the top ten research priorities
for chronic or recurrent urinary tract infections (UTIs).
The priorities identify long-standing gaps in knowledge related to diagnosis
and treatment and set a clear direction for future research investment.
Putting people with lived experience at the heart of research
The priorities have been developed through a national, patient and practitioner-led process that placed people with lived experience of the conditions at the heart of decision-making.
The priorities are an outcome of a pioneering partnership between AMR Action UK and the James Lind Alliance, alongside The Urology Foundation and Bladder Health UK.
UTIs can be experienced by anyone at any life stage. Up to half of all women will experience a UTI at some point in their life and of these, 20 to 50% will experience repeated episodes of UTI, or recurrent UTI.
For those living with chronic or recurrent infections, the impact on quality of life can be severe.
A recurrent UTI occurs when a person experiences multiple episodes of infection over time.
A chronic UTI involves persistent symptoms lasting over six months or even years. They can lead to difficulty working and withdrawal from social life.
UTIs are also one of the most common causes of sepsis, and vulnerable groups such as older adults and people with compromised immune systems face heightened risks.
Addressing the wider challenge of antimicrobial resistance
The research priorities show there are significant gaps in knowledge about the cause, prevalence, diagnosis, and treatment of chronic and recurrent UTIs.
By setting clear, patient-informed research priorities, the partnership ultimately aims to improve outcomes for people living with chronic or recurrent UTIs while helping to address the wider challenge of antimicrobial resistance.
Chronic and recurrent UTIs are a major driver of antibiotic use in the UK. Many patients experience repeated infections over months or even years, often receiving multiple courses of antibiotics that may offer only temporary relief. Without better diagnostic tools and more effective treatments, this cycle risks accelerating AMR, making infections harder, or in some cases impossible, to treat. In order to stem the threat of AMR, it is therefore crucial to have the right diagnostic tools available to ensure the right antibiotics are prescribed, and to ensure alternative therapies are developed.
Download the ten priorities here.
Download a table summary of the top ten here.
Download the full report here.
The full list of summary questions and the text submitted by survey respondents will be available at the JLA website.
Watch our webinar about the Top 10 priorities here.
